A New Level in Security: ISO 27001:2013

DNAnexus is pleased to announce it has updated its Information Security Management System (ISMS) to comply with the current ISO/IEC 27001:2013 standard. DNAnexus cloud-based services for secure genomic information management and analysis are implemented and delivered within the framework of this updated internationally recognized security standard.

In recent years, ISO/IEC 27001 and accompanying ISO/IEC 27002 (information security management controls) have been revised. The new version ISO/IEC 27001:2013 is the first revision since ISO/IEC 27001:2005 and puts more emphasis on measuring and evaluating how well an organization’s ISMS is performing.

DNAnexus has always taken a proactive approach to security and compliance. With the updated ISO 27001:2013 security standard, regulatory compliance has never been more robust, providing customers with the highest level of data security for both research and clinical use.

Interested in learning more about ISO 27001 or the DNAnexus platform’s compliance with HIPAA, CLIA, dbGaP, and EU Privacy? A number of detailed white papers on the subject are provided on the DNAnexus website.

DNAnexus Introduces Faster Cloud Options

Spring has arrived at DNAnexus, ushering in important updates! Starting May 1, 2014, we are excited to announce your analyses on DNAnexus will be faster, thanks to new instance types .

What does that really mean? Here’s an example before we dive into all the details…  A specific exome pipeline (e.g., BWA-MEM, GATK-Lite) now runs in less than 4 hours! Previously, the run would have taken nearly 6 hours.

New instance types

We believe, and hope you do too, that DNAnexus is the best choice for expanding your genomic analysis infrastructure. Because, unlike local equipment, which from day one starts collecting dust in your server room while technological advances pile up, the cloud is always on the forefront of computing technology as newer, faster hardware is made available.

These new hardware options are in the form of new instance types (virtual computer configurations) on which your cloud analyses can run. And thanks to the flexibility and reproducibility aspects of the DNAnexus platform, you can start using these new instance types right away—simply launch your existing analyses on one of those new instance types (e.g., using the “–instance-type <…>” option of our “dx run” command-line tool) and enjoy a completely effortless hardware upgrade!

The new instance types are built on high-frequency Intel® processors of the Sandy Bridge and Ivy Bridge microarchitectures, support the Intel® Advanced Vector Extensions (Intel® AVX), and have solid-state drive (SSD) local storage technology for fast I/O performance.

The following table summarizes these new instance types. For a given column (which represents a certain number of cores and local storage capacity), there are up to three different instance types to choose from (with different amounts of memory). Overall these new instance types span a large spectrum, starting at 2 cores, 32 GB SSD, and 3.8 GB RAM, all the way to 32 cores, 640 GB SSD, and 244 GB RAM:

summary new instance types
In an effort to be more informative and transparent, we have also come up with a new, easy to remember, and consistent naming scheme:

  • The prefix (mem1, mem2, or mem3) denotes the memory capacity per core;
  • the infix (ssd1) denotes that these instances have solid-state drive technology;
  • the suffix (x2 through x32) denotes the number of cores.


New names for existing instance types

We liked the convenient new naming scheme so much that we have applied it to existing instance types as well, as shown in the following table.

Compared to the new instance types mentioned earlier, the existing instance types are distinguished by a different storage infix (hdd2), given their regular hard disk drive technology. More information is available on our wiki page, which explains the new naming conventions and includes a detailed list of all instance types.

new instance names
To ease the transition, existing instances can currently be called by either their original name or the new name; the DNAnexus system understands both. However, we encourage you to adopt the new names in a timely manner to avoid any future interruption.

We are very excited to announce these important updates, and we cannot wait to hear your success stories out of them. Drop us a note at support@dnanexus.com if you’d like to get in touch with us.

Dev Talks: Genomics Applications in the Cloud with the DNAnexus Platform

The next public talk in our 2013 series will be at the University of Toronto’s, TCAG New Technologies Seminar. DNAnexus Sr. Software Engineer, Andrey Kislyuk, will conduct a brief demo of developing applications on the platform, as well as scientific collaboration, publishing, and reproducibility features.

Title: Building Genomics Applications in the Cloud with the DNAnexus Platform
When: Thursday, September 26, 2013
Time: 10:30–11:30 AM and 2:00-3:00 PM
Building: MaRS Toronto Medical Discovery Tower, 101 College St.
Room: 14-203

Abstract: The DNAnexus platform-as-a-service (PaaS) was designed to eliminate the common challenges and costs that enterprises face when building clinically compliant analysis pipelines for next-generation sequencing (NGS) data.  The DNAnexus platform provides a configurable API-based infrastructure that enables research labs to efficiently move their analysis pipelines into the cloud, using their own algorithms with industry-recognized tools and resources to create customized workflows in a secure and compliant environment.

DNAnexus is available to give on-site talks and demos to public and private institutions. Contact us for details at developers@dnanexus.com.
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